Advancements in Research and Treatment for Alzheimer's and Parkinson’s Disease

Alzheimer's and Parkinson's diseases are often perceived as neurodegenerative diseases caused by a fault in the nervous system. However, a vital insight is that these conditions arise when specific cells within the brain or nervous system have become weak or in a state of coma, impacting their ability to function and generate new cells.

Understanding Neurodegeneration

When ten cells in a specific area fail to receive adequate nutrition, they cease to function and produce energy. This critical condition leads to the formation of coma cells that inhibit the development of new cells. Coma cells can also induce insulin resistance, featuring a scenario where the brain cells no longer respond effectively to insulin—a common driver of type 2 diabetes. This pathology reflects the need for research to either rejuvenate these cells or remove them from the brain to restore proper functioning.

Current approaches in research and treatment primarily focus on managing symptoms and addressing middle events, rather than the fundamental causes. Instead, the emphasis should be on awakening or removing these coma cells to promote the development of new, healthy cells.

Treatment Approaches in Neurodegenerative Diseases

Engineering medicine diagnostics and combining it with homeopathic and naturopathic treatments can offer promising therapeutic options. Dr. SP Sharma suggests consulting online for these alternative treatments, as they provide a holistic approach to managing neurodegenerative diseases.

The Mechanisms of Neurodegenerative Diseases

The progression of these diseases can be attributed to a variety of factors, including environmental influences, neuroinflammation, metabolic stress, and genetic contributions.

Environmental contributions: These factors play a significant role in the progression of neurodegenerative diseases through cellular and epigenetic changes. Neuroinflammation: The effects of inflammation on the central nervous system (CNS) can range from neuroprotective to neurodegenerative, depending on the location, timing, and duration of the inflammatory response. Metabolic stress: Aging cells experience mitochondrial dysfunction, contributing to metabolic stress. This dysfunction can also impact the immune system and overall cellular health. Neurovascular coupling: Issues in the neurovascular system, such as glaucoma, can affect the visual system and exacerbate neurodegeneration. Genetic contributions: The apolipoprotein E ε4 (APOE4) allele significantly increases the risk of developing Alzheimer's disease.

Treatment Options for Neurodegenerative Diseases

Currently, several treatment options targeting glaucoma, such as IOP-lowering drops and surgery, can alleviate some symptoms of both Alzheimer's and Parkinson's diseases. Other promising research areas include:

Identifying molecular commonalities: Understanding shared molecular pathways can lead to the development of more effective and broadly applicable treatments for multiple neurodegenerative diseases. Understanding neuroinflammatory events: This knowledge can help identify how inflammation contributes to the progression of these diseases across various populations. Investigating prodromal and secondary inflammatory responses: These studies aim to understand how early and secondary inflammatory responses within cells expressing disease markers contribute to the overall pathology.

By focusing on the root causes and developing targeted therapies, researchers and clinicians can hopefully offer more effective treatments and prevent the progression of Alzheimer's and Parkinson's diseases in the future.